human PLCD3 Over-expression AAV

Cat. No: AAV-219122

Availability: 3-5 weeks

Name: AAV-h-PLCD3

This is an AAV expressing Human PLCD3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PLCD3
Gene Name: phospholipase C delta 3
Gene ID: 113026
Gene Synonyms: PLC-delta-3
ORF Size: 2370 bp
RefSeq#: BC072384
Gene Description: PLCD3 encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
UniGene ID: Hs.380094
HGNC ID: HGNC:9061