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human PLCD3 shRNA silencing Adenovirus

Name 
Ad-h-PLCD3-shRNA
Cat No 
shADV-219122
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PLCD3.

shADV-219122
Ad-h-PLCD3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PLCD3 (phospholipase C delta 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PLC-delta-3
Description (Vector)
PLCD3 encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
Gene ID
113026
Gene Name (Vector)
phospholipase C delta 3
Gene Symbol
PLCD3
HGNC ID
HGNC:9061
ORF Size (aa)
2370
ORF Size (bp)
2370 bp
RefSeq ID
NM_133373
RefSeq Synonyms
NM_133373, BC072384,
Species
human
UniGene ID
Hs.380094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.