human MS4A1 shRNA silencing AAV

Cat. No: shAAV-215884

Availability: 6-8 weeks

Name: AAV-h-MS4A1-shRNA

This is an AAV expressing shRNA for silencing of Human MS4A1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MS4A1
Gene Name: membrane spanning 4-domains A1
Gene ID: 931
Gene Synonyms: B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7
ORF Size: 894 bp
RefSeq#: NM_021950
Gene Description: MS4A1 encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A1 encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
UniGene ID: Hs.712553
HGNC ID: HGNC:7315