human MS4A1 Over-expression AAV

Name 
AAV-h-MS4A1
Cat No 
AAV-215884
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MS4A1.

AAV-215884
AAV-h-MS4A1

Ready-to-use AAV expressing Human MS4A1 (membrane spanning 4-domains A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B1; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; CD antigen CD20; CD20; CD20 antigen; CD20 receptor; CVID5; LEU-16; leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; MS4A2; S7
Description (eCommerce)
CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 is a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells [taken from NCBI Entrez Gene (Gene ID: 931)].
Description (Vector)
MS4A1 encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A1 encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Gene ID
931
Gene Name (eCommerce)
membrane spanning 4-domains A1
Gene Name (Vector)
membrane spanning 4-domains A1
Gene Symbol
MS4A1
HGNC ID
HGNC:7315
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
894
ORF Size (bp)
894 bp
Protein Name (eCommerce)
B-lymphocyte antigen CD20
RefSeq ID
NM_021950
RefSeq Synonyms
NM_152866, NM_021950, BC002807,
Research Areas
Immunology
Research Areas (Faceted)
immunology
Species
human
Target Sentence
CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 is a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells [taken from NCBI Entrez Gene (Gene ID: 931)].
UniGene ID
Hs.712553
UniProt ID (eCommerce)
P11836

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.