mouse ZBTB7B shRNA silencing AAV

Cat. No: shAAV-276539

Availability: 6-8 weeks

Name: AAV-m-ZBTB7B-shRNA

This is an AAV expressing shRNA for silencing of Mouse Zbtb7b.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Zbtb7b
Gene Name: zinc finger and BTB domain containing 7B
Gene ID: 22724
Gene Synonyms: c-Krox; Thpok; Zfp67
ORF Size: 1635 bp
RefSeq#: NM_009565
Gene Description: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity).
UniGene ID: Mm.262184