human KCNH2 shRNA silencing AAV

Cat. No: shAAV-212697

Availability: 6-8 weeks

Name: AAV-h-KCNH2-shRNA

This is an AAV expressing shRNA for silencing of Human KCNH2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNH2
Gene Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Gene ID: 3757
Gene Synonyms: ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1
ORF Size: 2460 bp
RefSeq#: NM_000238
Gene Description: KCNH2 encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.
UniGene ID: Hs.647099
HGNC ID: HGNC:6251