human NT5C3 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NT5C3A

Gene Name

5'-nucleotidase, cytosolic IIIA

Gene ID

51251

Gene Synonyms

cN-III; hUMP1; NT5C3; p36; P5'N-1; P5N-1; PN-I; POMP; PSN1; UMPH; UMPH1

ORF Size

894 bp

RefSeq#

NM_016489

Gene Description

NT5C3 encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in this gene are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and pseudogenes of this gene are located on the long arm of chromosomes 3 and 4.

UniGene ID

Hs.487933

HGNC ID

HGNC:17820