human AGAP2 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

AGAP2

Gene Name

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Gene ID

116986

Gene Synonyms

CENTG1; GGAP2; PIKE

ORF Size

2511 bp

RefSeq#

NM_014770

Gene Description

AGAP2 belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniGene ID

Hs.632854

HGNC ID

HGNC:16921