mouse SQSTM1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-273112
Availability:
Immediate
Name:
AAV-m-SQSTM1
This is an AAV expressing Mouse Sqstm1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Sqstm1
- Gene Name
- sequestosome 1
- Gene ID
- 18412
- Gene Synonyms
- A170; OSF-6; Osi; p62; STAP; STONE14
- ORF Size
- 1215 bp
- RefSeq#
- BC006019
- Gene Description
- Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
- UniGene ID
- Mm.40828
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