human AES Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-200523
Availability:
3-5 weeks
Name:
AAV-h-AES
This is an AAV expressing Human AES.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- AES
- Gene Name
- amino-terminal enhancer of split
- Gene ID
- 166
- Gene Synonyms
- AES-1; AES-2; ESP1; GRG; Grg-5; GRG5; TLE5
- ORF Size
- 795 bp
- RefSeq#
- BC113737
- Gene Description
- AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.515053
- HGNC ID
- HGNC:307
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