rat JMJD5 Over-expression AAV

Cat. No: AAV-294378

Availability: 3-5 weeks

Name: AAV-r-JMJD5

This is an AAV expressing Rat Kdm8.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Kdm8
Gene Name: lysine demethylase 8
Gene ID: 308976
Gene Synonyms: Jmjd5; RGD1304823
ORF Size: 1245 bp
RefSeq#: BC100627
Gene Description: Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.