mouse JMJD5 Over-expression AAV

Name 
AAV-m-JMJD5
Cat No 
AAV-262521
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Kdm8.

AAV-262521
AAV-m-JMJD5

Ready-to-use AAV expressing Mouse Kdm8 (lysine (K)-specific demethylase 8). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3110005O21Rik; Jmjd5
Description (Vector)
Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
Gene ID
77035
Gene Name (Vector)
lysine (K)-specific demethylase 8
Gene Symbol
Kdm8
ORF Size (aa)
1245
ORF Size (bp)
1245 bp
RefSeq ID
NM_029842
RefSeq Synonyms
NM_029842, BC024807,
Species
mouse
UniGene ID
Mm.307239

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.