human SULF2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-224703
Availability:
3-5 weeks
Name:
AAV-h-SULF2
This is an AAV expressing Human SULF2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SULF2
- Gene Name
- sulfatase 2
- Gene ID
- 55959
- Gene Synonyms
- HSULF-2
- ORF Size
- 2613 bp
- RefSeq#
- BC110539
- Gene Description
- Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 (PubMed 16192265)).(supplied by OMIM, Mar 2008)
- UniGene ID
- Hs.162016
- HGNC ID
- HGNC:20392
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