human TOLLIP Over-expression AAV

Name
AAV-h-TOLLIP

Cat No
AAV-226174

Availability
4-5 weeks

This is an AAV expressing Human TOLLIP.

AAV-226174

AAV-h-TOLLIP

Ready-to-use AAV expressing Human TOLLIP (toll interacting protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IL-1RAcPIP

Description (Vector)

TOLLIP encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase.

Gene ID

54472

Gene Name (Vector)

toll interacting protein

Gene Symbol

TOLLIP

HGNC ID

HGNC:16476

ORF Size (aa)

825

RefSeq ID

NM_019009

RefSeq Synonyms

NM_019009, NM_001318516, NM_001318515, NM_001318514, NM_001318512, BC018272, BC012057, BC004420,

Species

human

UniGene ID

Hs.368527

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.