human HTRA4 Over-expression AAV

Cat. No: AAV-211717

Availability: 3-5 weeks

Name: AAV-h-HTRA4

This is an AAV expressing Human HTRA4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HTRA4
Gene Name: HtrA serine peptidase 4
Gene ID: 203100
ORF Size: 1431 bp
RefSeq#: BC057765
Gene Description: HTRA4 encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.
UniGene ID: Hs.661014
HGNC ID: HGNC:26909