human EGFR Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-207663
Availability:
3-5 weeks
Name:
AAV-h-EGFR
This is an AAV expressing Human EGFR.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- EGFR
- Gene Name
- epidermal growth factor receptor
- Gene ID
- 1956
- Gene Synonyms
- ERBB; ERBB1; HER1; mENA; NISBD2; PIG61
- ORF Size
- 3276 bp
- RefSeq#
- BC094761
- Gene Description
- EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
- UniGene ID
- Hs.488293
- HGNC ID
- HGNC:3236
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