human EGFR shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-207663
Availability:
3-5 weeks
Name:
Ad-h-EGFR-shRNA
This is an Adenovirus expressing shRNA for silencing of Human EGFR.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- EGFR
- Gene Name
- epidermal growth factor receptor
- Gene ID
- 1956
- Gene Synonyms
- ERBB; ERBB1; HER1; mENA; NISBD2; PIG61
- ORF Size
- 3276 bp
- RefSeq#
- NM_005228
- Gene Description
- EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
- UniGene ID
- Hs.488293
- HGNC ID
- HGNC:3236
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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