human PDCD1 Over-expression AAV

Cat. No: AAV-218432

Availability: 3-5 weeks

Name: AAV-h-PDCD1

This is an AAV expressing Human PDCD1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDCD1
Gene Name: programmed cell death 1
Gene ID: 5133
Gene Synonyms: CD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
ORF Size: 867 bp
RefSeq#: BC074740
Gene Description: PDCD1 encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
UniGene ID: Hs.158297
HGNC ID: HGNC:8760