human PROC Over-expression AAV

Cat. No: AAV-219921

Availability: 3-5 weeks

Name: AAV-h-PROC

This is an AAV expressing Human PROC.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PROC
Gene Name: protein C, inactivator of coagulation factors Va and VIIIa
Gene ID: 5624
Gene Synonyms: APC; PC; PROC1; THPH3; THPH4
ORF Size: 1386 bp
RefSeq#: BC034377
Gene Description: PROC encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
UniGene ID: Hs.224698
HGNC ID: HGNC:9451