human MC2R Over-expression AAV

Name
AAV-h-MC2R

Cat No
AAV-215132

Availability
4-5 weeks

This is an AAV expressing Human MC2R.

AAV-215132

AAV-h-MC2R

Ready-to-use AAV expressing Human MC2R (melanocortin 2 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACTHR

Description (Vector)

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.

Gene ID

4158

Gene Name (Vector)

melanocortin 2 receptor

Gene Symbol

MC2R

HGNC ID

HGNC:6930

ORF Size (aa)

894

ORF Size (bp)

894 bp

RefSeq ID

NM_000529

RefSeq Synonyms

NM_001291911, NM_000529, BC104169, BC094710, BC069074,

Species

human

UniGene ID

Hs.248144

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.