catenin (beta) adenovirus
Product Name: Ad-CMV-catenin (beta)
Product Category: Ready-use human Adenovirus Type5 (dE1/E3)
Description: The catenins, α , β and γ , are proteins which bind to the highly conserved,
intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin
complexes play an important role mediating cellular adhesion. α-catenin, a
102 kDa protein, was initially described as an E-cadherin associated protein,
and since has been shown to associate with other members of the cadherin
family, such as N-cadherin and P-cadherin. The 92 kDa β-catenin associates
with the cytoplasmic portion of E-cadherin, which is necessary for the func-tion
of E-cadherin as an adhesion molecule. β-catenin has also been found
in complexes with the tumor suppressor protein APC. γ-catenin, also known
as plakoglobin, is an 82 kDa protein that binds with α-catenin and N-cad-herin.
Titer: 1x1010 PFU/ml
Volume: 200ul
Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol
Availability: In stock, same day shipping available for orders placed before 1PM.
References: - Wnt/Beta-Catenin Signaling Is Involved In Regulation Of Osteoclast Differentiation By Human Immunodeficiency Virus Protease Inhibitor Ritonavir: Relationship To Human Immunodeficiency Virus-Linked Bone Mineral Loss.
Am J Pathol.. 2009. 174(1):123-35 - Downregulated Microrna-200a In Meningiomas Promotes Tumor Growth By Reducing E-Cadherin And Activating The Wnt/Beta-Catenin Signaling Pathway.
Molecular and Cellular Biology. 2009. 29(21):5923-40.
| Catalog No. |
Tag |
Promoter |
|
Species |
Price ** |
 |
| 1182 |
GFP |
CMV |
|
|
$475.00 |
|