mouse PYCARD shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Pycard

Gene Name

PYD and CARD domain containing

Gene ID

66824

Gene Synonyms

9130417A21Rik; Asc; CARD5; masc; TMS-1; TNS1

ORF Size

582 bp

RefSeq#

NM_023258

Gene Description

Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

UniGene ID

Mm.24163