mouse ORF19 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Washc1

Gene Name

WASH complex subunit 1

Gene ID

68767

Gene Synonyms

1110049F14Rik; ORF19; Wash; Wash1

ORF Size

1428 bp

RefSeq#

NM_001037757

Gene Description

Acts as a nucleation-promoting factor at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.

UniGene ID

Mm.296545