mouse KCNN4 shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Kcnn4

Gene Name

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene ID

16534

Gene Synonyms

IK1; IKCA1; KCa3.1; KCA4; mIKCa1; SK4; SKCas

ORF Size

1278 bp

RefSeq#

NM_008433

Gene Description

Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.

UniGene ID

Mm.9911