mouse KCNN4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kcnn4.
shAAV-262701
AAV-m-KCNN4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kcnn4 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IK1; IKCA1; KCa3.1; KCA4; mIKCa1; SK4; SKCas
Description (Vector)
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Gene ID
16534
Gene Name (Vector)
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Gene Symbol
Kcnn4
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_008433
RefSeq Synonyms
NM_008433, NM_001163510, BC010274,
Species
mouse
UniGene ID
Mm.9911
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.