mouse KCNN4 shRNA silencing Adenovirus

Name 
Ad-m-KCNN4-shRNA
Cat No 
shADV-262701
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Kcnn4.

shADV-262701
Ad-m-KCNN4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kcnn4 (potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IK1; IKCA1; KCa3.1; KCA4; mIKCa1; SK4; SKCas
Description (Vector)
Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.
Gene ID
16534
Gene Name (Vector)
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Gene Symbol
Kcnn4
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_008433
RefSeq Synonyms
NM_008433, NM_001163510, BC010274,
Species
mouse
UniGene ID
Mm.9911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.