mouse ESRP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Esrp1.
shADV-258718
Ad-m-ESRP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Esrp1 (epithelial splicing regulatory protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2210008M09Rik; A630065D16; BC031468; Rbm35a
Description (Vector)
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Gene ID
207920
Gene Name (Vector)
epithelial splicing regulatory protein 1
Gene Symbol
Esrp1
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_194055
RefSeq Synonyms
NM_194055, NM_001347052, NM_001290383, BC031468,
Species
mouse
UniGene ID
Mm.387719
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.