mouse EIF2S1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Eif2s1.
shADV-258193
Ad-m-EIF2S1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Eif2s1 (eukaryotic translation initiation factor 2, subunit 1 alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0910001O23Rik; 2410026C18Rik; 35kDa; Eif2a; eIF2alpha
Description (Vector)
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Gene ID
13665
Gene Name (Vector)
eukaryotic translation initiation factor 2, subunit 1 alpha
Gene Symbol
Eif2s1
ORF Size (aa)
948
ORF Size (bp)
948 bp
RefSeq ID
NM_026114
RefSeq Synonyms
NM_026114, BC016497, BC016448, BC005463,
Species
mouse
UniGene ID
Mm.196220
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.