human PRSS1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PRSS1

Gene Name

protease, serine 1

Gene ID

5644

Gene Synonyms

TRP1; TRY1; TRY4; TRYP1

ORF Size

744 bp

RefSeq#

NM_002769

Gene Description

PRSS1 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. PRSS1 and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

UniGene ID

Hs.654498

HGNC ID

HGNC:9475