human KAT2A shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

KAT2A

Gene Name

lysine acetyltransferase 2A

Gene ID

2648

Gene Synonyms

GCN5; GCN5L2; hGCN5; PCAF-b

ORF Size

2514 bp

RefSeq#

NM_021078

Gene Description

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 (PubMed 19339690)).(supplied by OMIM, Sep 2009)

UniGene ID

Hs.463045

HGNC ID

HGNC:4201