mouse KAT2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Kat2a.
shAAV-262567
AAV-m-KAT2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Kat2a (K(lysine) acetyltransferase 2A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110051E14Rik; AW212720; Gcn5; Gcn5l2; mmGCN5
Description (Vector)
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Gene ID
14534
Gene Name (Vector)
K(lysine) acetyltransferase 2A
Gene Symbol
Kat2a
ORF Size (aa)
2490
ORF Size (bp)
2490 bp
RefSeq ID
NM_020004
RefSeq Synonyms
NM_020004, NM_001038010, BC063752,
Species
mouse
UniGene ID
Mm.218837
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.