human GIGYF2 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GIGYF2

Gene Name

GRB10 interacting GYF protein 2

Gene ID

26058

Gene Synonyms

GYF2; PARK11; PERQ2; PERQ3; TNRC15

ORF Size

3963 bp

RefSeq#

NM_015575

Gene Description

GIGYF2 interacts with GRB10 and may be involved in the regulation of tyrosine kinase receptor signaling. This gene contains CAG repeats, and the encoded protein contains stretches glutamine and glutamic acid residues. Defects in this gene are a cause of Parkinson disease type 11 (PARK11). Multiple transcript variants encoding several different isoforms have been found for this gene.

UniGene ID

Hs.565319

HGNC ID

HGNC:11960