human DUOX1 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-207394
Availability:
5-8 weeks
Name:
Ad-h-DUOX1-shRNA
This is an Adenovirus expressing shRNA for silencing of Human DUOX1.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DUOX1
- Gene Name
- dual oxidase 1
- Gene ID
- 53905
- Gene Synonyms
- LNOX1; NOXEF1; THOX1
- ORF Size
- 4656 bp
- RefSeq#
- NM_017434
- Gene Description
- DUOX1 is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
- UniGene ID
- Hs.272813
- HGNC ID
- HGNC:3062
Related Products
Product | Cat No. |
---|---|
Ad-h-DUOX1 | ADV-207394 |
Ad-m-DUOX1 | ADV-257515 |
AAV-h-DUOX1-shRNA | shAAV-207394 |
AAV-m-DUOX1-shRNA | shAAV-257515 |
Ad-m-DUOX1-shRNA | shADV-257515 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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