human ADH7 shRNA silencing Adenovirus

Cat. No: shADV-200463

Availability: 5-8 weeks

Name: Ad-h-ADH7-shRNA

This is an Adenovirus expressing shRNA for silencing of Human ADH7.

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Species: Human
Gene Symbol: ADH7
Gene Name: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Gene ID: 131
Gene Synonyms: ADH4
ORF Size: 1161 bp
RefSeq#: NM_000673
Gene Description: ADH7 encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.389
HGNC ID: HGNC:256