rat HERC4 shRNA silencing AAV

Cat. No: shAAV-292479

Availability: 4-5 weeks

Name: AAV-r-HERC4-shRNA

This is an AAV expressing shRNA for silencing of Rat Herc4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Rat
Gene Symbol: Herc4
Gene Name: HECT and RLD domain containing E3 ubiquitin protein ligase 4
Gene ID: 309758
ORF Size: 3174 bp
RefSeq#: NM_001012074
Gene Description: Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity).