mouse TICAM2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-281160
Availability:
6-8 weeks
Name:
AAV-m-TICAM2-shRNA
This is an AAV expressing shRNA for silencing of Mouse Ticam2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Ticam2
- Gene Name
- toll-like receptor adaptor molecule 2
- Gene ID
- 225471
- Gene Synonyms
- B430113A10; TICAM-2; Tirp; TRAM; Trif
- ORF Size
- 699 bp
- RefSeq#
- NM_173394
- Gene Description
- Functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Also involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1.
- UniGene ID
- Mm.149280
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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