mouse CLIC4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-280643
Availability:
Immediate
Name:
AAV-m-CLIC4-shRNA
This is an AAV expressing shRNA for silencing of Mouse Clic4.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Clic4
- Gene Name
- chloride intracellular channel 4 (mitochondrial)
- Gene ID
- 29876
- Gene Synonyms
- D0Jmb3; mc3s5; mtCLIC; TU-74
- ORF Size
- 762 bp
- RefSeq#
- NM_013885
- Gene Description
- Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
- UniGene ID
- Mm.473864
Related Products
Product | Cat No. |
---|---|
AAV-h-CLIC4 | AAV-205454 |
AAV-m-CLIC4 | AAV-255654 |
Ad-h-CLIC4 | ADV-205454 |
Ad-m-CLIC4 | ADV-255654 |
AAV-h-CLIC4-shRNA | shAAV-205454 |
Ad-h-CLIC4-shRNA | shADV-205454 |
Ad-m-CLIC4-shRNA | shADV-280643 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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