mouse CLIC4 Over-expression AAV

Name 
AAV-m-CLIC4
Cat No 
AAV-255654
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Clic4.

AAV-255654
AAV-m-CLIC4

Ready-to-use AAV expressing Mouse Clic4 (chloride intracellular channel 4 (mitochondrial)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D0Jmb3; mc3s5; mtCLIC; TU-74
Description (Vector)
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Promotes cell-surface expression of HRH3. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).
Gene ID
29876
Gene Name (Vector)
chloride intracellular channel 4 (mitochondrial)
Gene Symbol
Clic4
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_013885
RefSeq Synonyms
NM_013885, BC052890, BC046384,
Species
mouse
UniGene ID
Mm.473864

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.