mouse TIPRL shRNA silencing AAV

Cat. No: shAAV-274241

Availability: 4-5 weeks

Name: AAV-m-TIPRL-shRNA

This is an AAV expressing shRNA for silencing of Mouse Tiprl.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tiprl
Gene Name: TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Gene ID: 226591
Gene Synonyms: 1810011K17Rik
ORF Size: 816 bp
RefSeq#: NM_145513
Gene Description: TIPRL may be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair.
UniGene ID: Mm.21520