mouse KHDRBS2 shRNA silencing AAV

Cat. No: shAAV-262784

Availability: 6-8 weeks

Name: AAV-m-KHDRBS2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Khdrbs2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Khdrbs2
Gene Name: KH domain containing, RNA binding, signal transduction associated 2
Gene ID: 170771
Gene Synonyms: 6330586C16Rik; Slim1; Slm1
ORF Size: 1050 bp
RefSeq#: NM_133235
Gene Description: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).
UniGene ID: Mm.336594