mouse KDM5B shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-262769
Availability:
Immediate
Name:
AAV-m-KDM5B-shRNA
This is an AAV expressing shRNA for silencing of Mouse Kdm5b.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Kdm5b
- Gene Name
- lysine (K)-specific demethylase 5B
- Gene ID
- 75605
- Gene Synonyms
- 2010009J12Rik; 2210016I17Rik; AW556288; D1Ertd202e; Jarid1b; mKIAA4034; PLU-1; Plu1; PUT1; Rb-Bp2; RBBP2H1A
- ORF Size
- 4635 bp
- RefSeq#
- NM_152895
- Gene Description
- Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.
- UniGene ID
- Mm.391994
Related Products
Product | Cat No. |
---|---|
Ad-h-KDM5B | ADV-212851 |
Ad-h-KDM5B | ADV-212852 |
Ad-m-KDM5B | ADV-262769 |
AAV-h-KDM5B-shRNA | shAAV-212852 |
Ad-h-KDM5B-shRNA | shADV-212852 |
Ad-m-KDM5B-shRNA | shADV-262769 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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