mouse KDM5B shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-262769
Availability:
3-5 weeks
Name:
Ad-m-KDM5B-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Kdm5b.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Kdm5b
- Gene Name
- lysine (K)-specific demethylase 5B
- Gene ID
- 75605
- Gene Synonyms
- 2010009J12Rik; 2210016I17Rik; AW556288; D1Ertd202e; Jarid1b; mKIAA4034; PLU-1; Plu1; PUT1; Rb-Bp2; RBBP2H1A
- ORF Size
- 4635 bp
- RefSeq#
- NM_152895
- Gene Description
- Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma.
- UniGene ID
- Mm.391994
Related Products
Product | Cat No. |
---|---|
Ad-h-KDM5B | ADV-212851 |
Ad-h-KDM5B | ADV-212852 |
Ad-m-KDM5B | ADV-262769 |
AAV-h-KDM5B-shRNA | shAAV-212852 |
AAV-m-KDM5B-shRNA | shAAV-262769 |
Ad-h-KDM5B-shRNA | shADV-212852 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy