mouse IL1R1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-262138
Availability:
Immediate
Name:
AAV-m-IL1R1-shRNA
This is an AAV expressing shRNA for silencing of Mouse Il1r1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Il1r1
- Gene Name
- interleukin 1 receptor, type I
- Gene ID
- 16177
- Gene Synonyms
- CD121a; CD121b; IL-1R1; IL-iR; Il1r-1
- ORF Size
- 1731 bp
- RefSeq#
- NM_008362
- Gene Description
- Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
- UniGene ID
- Mm.896
Related Products
Product | Cat No. |
---|---|
AAV-h-IL1R1 | AAV-212104 |
AAV-m-IL1R1 | AAV-262138 |
Ad-h-IL1R1 | ADV-212104 |
Ad-m-IL1R1 | ADV-262138 |
AAV-h-IL1R1-shRNA | shAAV-212104 |
Ad-h-IL1R1-shRNA | shADV-212104 |
Ad-m-IL1R1-shRNA | shADV-262138 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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