mouse IL1R1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-262138
Availability:
3-5 weeks
Name:
AAV-m-IL1R1
This is an AAV expressing Mouse Il1r1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Il1r1
- Gene Name
- interleukin 1 receptor, type I
- Gene ID
- 16177
- Gene Synonyms
- CD121a; CD121b; IL-1R1; IL-iR; Il1r-1
- ORF Size
- 1731 bp
- RefSeq#
- BC109135
- Gene Description
- Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
- UniGene ID
- Mm.896
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