mouse GRK4 shRNA silencing AAV

Cat. No: shAAV-260781

Availability: 6-8 weeks

Name: AAV-m-GRK4-shRNA

This is an AAV expressing shRNA for silencing of Mouse Grk4.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Grk4
Gene Name: G protein-coupled receptor kinase 4
Gene ID: 14772
Gene Synonyms: A830025H08Rik; Gprk2l; Gprk4; GRK
ORF Size: 1725 bp
RefSeq#: NM_019497
Gene Description: Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2.
UniGene ID: Mm.117076