mouse FOXO4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Foxo4.
shAAV-259592
AAV-m-FOXO4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Foxo4 (forkhead box O4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
afx; Afxh; Mllt7
Description (Vector)
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
Gene ID
54601
Gene Name (Vector)
forkhead box O4
Gene Symbol
Foxo4
ORF Size (aa)
1518
ORF Size (bp)
1518 bp
RefSeq ID
NM_018789
RefSeq Synonyms
NM_018789, BC139304, BC139275,
Species
mouse
UniGene ID
Mm.371606
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.