mouse CACNA1G shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-254366
Availability:
Immediate
Name:
AAV-m-CACNA1G-shRNA
This is an AAV expressing shRNA for silencing of Mouse Cacna1g.
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Product Info
- Knockdown
- >50% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Cacna1g
- Gene Name
- calcium channel, voltage-dependent, T type, alpha 1G subunit
- Gene ID
- 12291
- Gene Synonyms
- a1G; alpha-1G; Cav3.1d; mKIAA1123; [a]1G
- ORF Size
- 6747 bp
- RefSeq#
- NM_009783
- Gene Description
- Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
- UniGene ID
- Mm.29585
Related Products
Product | Cat No. |
---|---|
Ad-h-CACNA1G | ADV-203903 |
Ad-m-CACNA1G | ADV-254366 |
AAV-h-CACNA1G-shRNA | shAAV-203903 |
Ad-h-CACNA1G-shRNA | shADV-203903 |
Ad-m-CACNA1G-shRNA | shADV-254366 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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