mouse CACNA1G shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cacna1g.
shADV-254366
Ad-m-CACNA1G-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cacna1g (calcium channel, voltage-dependent, T type, alpha 1G subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
a1G; alpha-1G; Cav3.1d; mKIAA1123; [a]1G
Description (Vector)
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channels is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Gene ID
12291
Gene Name (Vector)
calcium channel, voltage-dependent, T type, alpha 1G subunit
Gene Symbol
Cacna1g
ORF Size (aa)
6747
ORF Size (bp)
6747 bp
RefSeq ID
NM_009783
RefSeq Synonyms
NM_009783, NM_001177890, NM_001177888, NM_001112813, BC057399,
Species
mouse
UniGene ID
Mm.29585
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.