human ATP2B2 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-233936
Availability:
6-8 weeks
Name:
AAV-h-ATP2B2-shRNA
This is an AAV expressing shRNA for silencing of Human ATP2B2.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ATP2B2
- Gene Name
- ATPase plasma membrane Ca2+ transporting 2
- Gene ID
- 491
- Gene Synonyms
- PMCA2; PMCA2a; PMCA2i
- ORF Size
- 3732 bp
- RefSeq#
- NM_001001331
- Gene Description
- ATP2B2 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
- HGNC ID
- HGNC:815
Related Products
Product | Cat No. |
---|---|
AAV-m-ATP2B2 | AAV-253283 |
Ad-h-ATP2B2 | ADV-233936 |
Ad-m-ATP2B2 | ADV-253283 |
AAV-m-ATP2B2-shRNA | shAAV-253283 |
Ad-h-ATP2B2-shRNA | shADV-233936 |
Ad-m-ATP2B2-shRNA | shADV-253283 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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