human DAZ3 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-232725
Availability:
6-8 weeks
Name:
AAV-h-DAZ3-shRNA
This is an AAV expressing shRNA for silencing of Human DAZ3.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- DAZ3
- Gene Name
- deleted in azoospermia 3
- Gene ID
- 57054
- Gene Synonyms
- pDP1679
- ORF Size
- 1317 bp
- RefSeq#
- NM_020364
- Gene Description
- DAZ3 is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. DAZ3 contains one copy of the 10.8 kb repeat.
- UniGene ID
- Hs.
- HGNC ID
- HGNC:15965
Related Products
Product | Cat No. |
---|---|
AAV-h-DAZ3 | AAV-232725 |
Ad-h-DAZ3 | ADV-232725 |
Ad-h-DAZ3-shRNA | shADV-232725 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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